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. At our Center, researchers study the cellular mechanisms of health and disease in the central nervous system. The De Wit lab (Laboratory of Synapse Biology) at the VIB-KU Leuven Center for Brain & Disease
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for months, years, or even millennia. Our lab aims to resolve the molecular mechanisms behind this process, focusing on how promiscuous enzymes (un)intentionally transform cellular metabolites into degradation
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high potential to suppress disease expression and/or progression. Your job You will work with a team of scientists interested in (1) mechanisms of neurodegeneration, (2) cellular determinants of disease
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universities. At our Center, researchers study the cellular mechanisms of health and disease in the central nervous system. Dr. Esther Klingler started her lab in 2023 within the VIB-KU Leuven Center for Brain
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to identify and characterize these compounds. Additionally, microbial cell factories will be engineered for metabolite production through pathway engineering and dynamic pathway control. The postdoctoral
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to be associated with a typical XBP1-driven gene signature (Osorio et al, Nat Imm, 2014 and Tavernier et al., Nat Cell Biol, 2017), but rather with RIDD, and appears closely linked with apoptotic cell
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single-cell and spatial multi-omics datasets. The primary focus of this role is to delve deeper into the molecular mechanisms driving intra-tumor heterogeneity, plasticity, and therapy resistance
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and/or comparable expertise (e.g from industry). Demonstrated expertise in omics data analysis, for example with (meta)genomics, transcriptomics, proteomics, metabolomics, single cell and/or genotyping