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on cells of the innate immune system such as macrophages and neutrophils. In particular, we explore mechanisms of malignant transformation, cellular differentiation and the control of immune cell
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cancer cell plasticity in AML. Our overall goal is to pave the way for new cancer therapies. In our project we want to decipher the niche-related adaptive molecular mechanisms that underlie and promote
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biology and great enthusiasm for the bone marrow niche and therapy-resistance mechanisms. The PhD student will work in close collaboration with other CRC/SFB members and groups and will perform multiomics
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Malignancies: From Mechanisms to Therapies”. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate cancer cell plasticity in AML. Our
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Max Planck Institute for Multidisciplinary Sciences, Göttingen | Gottingen, Niedersachsen | Germany | 15 days ago
40 research groups and some 1,000 employees from over 50 nations, it is the largest institute of the Max Planck Society . The research group Molecular Mechanisms of Membrane Trafficking (Dr. Oleksiy
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1,000 employees from over 50 nations, it is the largest institute of the Max Planck Society . The research group Molecular Mechanisms of Membrane Trafficking (Dr. Oleksiy Kovtun) at the City Campus
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project “Plastic growth behaviour of patients’ AML in vivo: Releasing dormant cells from their protective niche.” We are an interdisciplinary and collaborative research team at the forefront of multi-omics
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cell sequencing datasets and to combine these data with AI analyses from bone marrow smears. We aim to analyze mechanisms and also to develop new biomarkers for therapy response and resistance. Job-ID
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on uncovering mechanisms of CNS myelination and neuroinflammation. The lab combines advanced in vivo imaging approaches with complex models of demyelinating disease to investigate glial cell dynamics, immune-glia
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state of Rhineland-Palatinate. Our research focuses on the biology of the cell nucleus and ranges from the molecular level to systems and computational approaches. Researchers at IMB are supported by