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. In particular, they are involved in cell signaling pathways, acting as secondary messengers and enzyme cofactors. The development of non-natural mimics with improved pharmacokinetic and pharmacodynamic
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of the intracellular distribution of NPP aggregates, various stress parameters, and EMT markers. Finally, transcriptomic analyses will establish the molecular signatures of NPP exposure and identify the signaling
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importance through integration in cell membranes, as energy source and in cellular signaling and function. As such, they also play decisive roles in cardiovascular disease, chronic kidney disease, cancer and
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