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early risk identification. This PhD project aims to design and develop personalised 3D-printed insoles with enhanced offloading performance and integrated sensing capability. The work will explore novel
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the drivers behind this public health issue have not been identified. In this project, we will use a dataset of C. difficile genome sequences to generate a nationwide population snapshot of
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, precise and is pathogen agnostic, you don’t need prior knowledge of which pathogen is causing the infection to use it as a diagnostic. Challenges remain however in standardisation, application and
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. These events can reshape microbial communities and elevate the risk of human exposure to harmful pathogens. This project will use cutting-edge metagenomic, genomic and transcriptomic sequencing to investigate
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Main description: Native mass spectrometry is an expanding structural biology tool to elucidate the function of protein complexes. Excitingly, the demand for this technology is increasing. However
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performed directly on a clinical sample, removing the need for culture and often improving accuracy of diagnosis of the causative pathogen. Their use is also now becoming widespread for mass scale
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heating, ventilation, and appliance use, which need behavioural interventions like feedback and education. These behaviours influence how retrofits are adopted and maintained, causing performance gaps
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The ability of an organism to distinguish between self and non-self and to mount an effective response is the foundation of a functional immune system. The immune systems of animals and plants have
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Background: The proposed project has emerged from a long-standing interest in the signalling and repair functions of the BRCA1 and PALB2 tumour suppressors. Specifically, we have been investigating
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Project Outline Skeletal muscle undergoes progressive loss of mass and function during ageing, a process termed sarcopenia. This decline arises from reduced myogenesis and degeneration of existing