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genomes. Dr Karam Teixeira's group uses Drosophila as a model to study transposable element biology, epigenetic regulation and inheritance, small RNA-based defence mechanisms, and germline biology in
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rhabdomyosarcoma), fragmented data from multiple small series has hampered global elementary understanding of metastasis biology and - therefore – targeted therapy development. It remains unresolved – and is
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must either have a PhD in a relevant biological subject or have submitted or about to submit their PhD thesis. Candidates must also have demonstrable expertise in biochemistry, cell biology and/or
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Award summary This project will involve studying the mechanisms underlying Alpers’ syndrome, a devastating early-onset form of mitochondrial disease. The aim of the proposed studentship is to better understand the causes of the condition to facilitate the development of novel treatments. The...
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to
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other common conditions in pet dogs, then use comparative genomics to determine those genes also relevant to humans. Genes and variants responsible are studied in the molecular biology lab and by testing
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biology techniques (cryoEM and X-ray crystallography) to determine the structures of tyrosine fusion kinases found in leukaemia, and their complexes with the HSP90 molecular chaperone. Biochemistry and
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bioprocessing technologies to deliver efficient pathways for upcycling captured carbon into high value products. The successful candidate will have a PhD, or be studying towards a PhD, in synthetic biology or a
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limited options. Eligibility Applicants should have a first or upper second-class honours degree (or equivalent) in a relevant discipline, such as cell biology, biomedical sciences, immunology, molecular
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molecular biology, quantitative imaging and biophysical approaches to investigate cell shape changes in cultured cells and in vivo. Current projects in the lab include investigating the regulation