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Each year, approximately 6,000 people in the UK are diagnosed with multiple myeloma. Despite advances in therapy, infections remain a leading cause of morbidity and early mortality in these patients
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readouts Apply a wide spectrum of genetic, molecular, and cell biology, biochemical as well as micobial and bioinformatics techniques to study translational aspects of colon cancer (e.g., Cre/loxP and Flp
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readouts Apply a wide spectrum of genetic, molecular, and cell biology, biochemical as well as micobial and bioinformatics techniques to study translational aspects of colon cancer (e.g., Cre/loxP and Flp
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: How are multiple different RNP granules with individualized mRNA cargo maintained in MN axons? How much exchange of RNA-binding proteins occurs between different RNP granules within axons? How do RNP
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posed a challenge. I questioned my supervisor multiple times about the necessity of learning Dutch. Fortunately, she assured me that the English level is very high in Nijmegen and the Netherlands. When I
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mechanisms and pathways behind – multiple exposures pathogenesis and disease is not yet fully understood. In the EXPOSIM project, a large-scale EU project, we aim to unravel the complexity of the association
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approaches will be developed to design molecules from scratch and are expected balance interaction with multiple targets. Specific goals are: Development of a conditional generation approach for the de novo
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) or Multiple Myeloma (MM). However, in some cases like MM, there is a lack of long-term response, and in other malignant conditions, such as acute myeloid leukemia or solid tumors, the efficacy
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) to investigate how coastal temperate marine invertebrate and macroalgal species respond to extreme heat events, both marine and atmospheric, across multiple biological scales. You will: Conduct single-species
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mechanisms of the sexual conflict and its resolution. You will combine cutting-edge bioinformatics, genome engineering, and state-of-the-art sequencing technologies to: Identify and characterise consistent