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Field
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protein and peptide separation methods, cell culture and molecular biology labs, and bioinformatics infrastructure. The group has world-renown expertise in the analysis of intact (native) proteins
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brain connectome organization and the integration of this data with recent functional and structural connectome properties and recent evolutionary genetic discoveries, utilizing large-scale bioinformatic
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and Environment (A-LIFE) at the Vrije Universiteit Amsterdam invites applications for an exciting PhD position that will combine innovative bioinformatics and genomic tools to study genomic
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readouts such as Perturb-seq. Experience or familiarity with advanced genome editing methods such as prime editing, or base editing is highly desirable. Experience with bioinformatics data analysis using
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strategies; proven ability to design, execute, and troubleshoot pooled and/or arrayed CRISPR screens in mammalian cells; strong computational skills in bioinformatics and data analysis (e.g. R, Python
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with glycobiology, structural biology, or influenza evolution, for example using glycan interaction assays, bioinformatics tools, or structural models to refine hypotheses. Additional Information
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inference; make use of available and newly obtained omics datasets as input for your approaches; collaborate with both experimental researchers as well as with bioinformatics/systems biology researchers (e.g
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bioinformatic and AI tools to analyse the mass spectrometry data and improve the de novo sequencing workflows. Your work will lead to new antibody leads, that can be recombinantly produced and ultimately tested
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relevant to the chosen position (including biology, medicine, biochemistry, bioinformatics or a related discipline, depending on each PhD project) or its equivalent that would entitle them to a doctorate one
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proteomic technologies and bioinformatics are used. We run Next Generation Sequencers, single-cell platforms and mass spectrometers, and accommodate a bioinformatics team and a local computational