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@inserm.fr Requirements Research FieldBiological sciences » Biological engineeringEducation LevelPhD or equivalent Skills/Qualifications Main responsibilities: Bioinformatics, data indexing, large-scale
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to the bioinformatic and computational analysis of interactions between tumors and the immune system. Using large-scale genomics approaches and single-cell technologies (scRNA-seq, scATAC-seq, scTCR-seq), it explores
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bioinformatics approaches to human-relevant models and unique patient-derived tissue cohorts from colorectal cancer. The aim is to dissect the tumor "ecosystem" with a particular emphasis on epithelial cells
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at strengthening the interface between immunology, bioinformatics and gene expression regulation in a physiologic and tumor context. The analyses of genomic and transcriptomic datasets (public and internal to Curie
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and transcriptomic data that will be subjected to bioinformatic analysis to integrate and interpret complex datasets, helping us to better understand the underlying mechanisms of the disease. Our
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experiment. Finally, bioinformatics will be used to compare the sequences enriched in each experimental context (topology, addition of chemical modifications, medium composition). The most promising constructs
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to join the AI for Genome Interpretation (AI4GI) group at the IGMM (CNRS, Montpellier) for 18 months. The project is a collaboration between IGMM and IMAG, at the interface of genetics, bioinformatics
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, the recruited researcher will use molecular resources and develop bioinformatic tools to describe the taxonomic diversity of zooplankton communities for a series of lakes having been recently restored. Using
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stations for large-scale bioinformatic analysis, a cryo-EM microscope recently installed at the institute, as well as privileged access to state-of-the-art infrastructures: cryo-EM Titan Krios (ESRF
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to the Bioinformatics, Phylogeny and Evolutionary Genomics (BPGE- https://lbbe.univ-lyon1.fr/en/bioinformatics-phylogeny-and-evolutionary… ) team at the Laboratory of Biometry and Evolutionary Biology (LBBE) and will be