Sort by
Refine Your Search
-
Listed
-
Field
-
-consuming and often fail to express target proteins at sufficient levels. In this project, you will investigate whether mammalian cell lines can be genetically altered to enhance expression of challenging
-
learning, evidence synthesis in public health and statistical genetics and genomics. We are recognised for our strength in Bayesian inference applied to biomedicine and public health. The MRC Biostatistics
-
Bernardes on the control of ADC payload release. Antibody Drug Conjugates (ADCs) are a rapidly expanding class of targeted therapeutics. Much effort in the field has been devoted to the identification
-
development should be targeted. Evaluate the potential for blue/green and sustainable solutions for improvement to network performance. For project-specific enquiries please e-mail Professor Dongfang Liang
-
and validate AI-driven control strategies that optimise comfort and carbon reduction. Assess heat pump readiness and propose targeted interventions to facilitate low-carbon retrofits. Produce guidelines
-
Chemistry and Chemical Biology. The project will combine the advances in Antibody-drug conjugates (ADCs) with antisense oligonucleotides. ADCs have revolutionized targeted cancer therapy by delivering
-
(NP) led by Professor Jeremy J Baumberg, FRS (https://www.np.phy.cam.ac.uk/ ), as part of UK targeted collaboration on 3D Metamaterials. Metamaterials provide emergent properties by combining nano-scale
-
small molecule interactions with DNA, RNA and associated proteins. We are exploiting our findings from such methods to design bifunctional small molecules that target the genome and chromatin-associated
-
target, since all known treatment resistance mechanisms are downstream of, and dependent on FOXA1. However, FOXA1 has been a difficult protein to study for technical reasons. We have developed a novel tool
-
treatments that target AR have forced cancer cells to evade treatment and a newly characterised, but frequent escape mechanism is for cancer cells to lose dependence on AR and to take on features of a