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collaborate with various comprehensive cores at MDACC to develop novel therapeutic strategies that enhance targeted and immunotherapies. Dr. Chen is deeply committed to the professional fulfillment and career
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& Responsibilities - Overexpression and purification of target proteins for structural studies. - Biochemically and biophysically characterize interactions between proteins and their binding partners. - Design and
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development for brain disorders, leveraging stem cell-derived organoid models and gene targeting tools. Our recent work demonstrated that stem cell models offer a unique opportunity to study disease phenotypes
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to accelerate therapeutic development for brain disorders, leveraging stem cell-derived organoid models and gene targeting tools. Our recent work demonstrated that stem cell models offer a unique opportunity to
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Postdoctoral Research Associate - Basic and Translational Research Training in Pediatric Classical H
by training in the execution of statistically rigorous, hypothesis-driven research that probes the mechanistic basis of hematologic disease, uncovers new therapeutic targets, and translates
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to study hypotheses Validate models via targeted simulation, sensitivity analysis and exploration Apply methods to problems in geosciences, in particular bio-/geochemical cycles Your qualifications: A
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compartments. The aim of these studies is to identify host-targeted therapies that improve clinical outcome when initiated after the onset of critical illness, when many patients present for care. Fundamental
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cell populations which may involve targeted validation by working with a collaborator. Bulk tumor samples will include those of fresh-frozen material of pediatric cancer patients and archive FFPE RNA-seq
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. Recent work includes the discovery and structural characterization of novel dsDNA sensors and the identification of small molecules targeting key innate immune components https://doi.org/10.1016/j.cell
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challenging research and work in a highly collaborative manner. Projects will discover potential new targets to guide the personalized treatment of devastating human cancers of unmet need. For more information