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deacetylases, including SIRT1 and HDAC6, and ion channels to control signaling pathways impacting metabolism, apoptosis, and autism, and we leverage these discoveries to develop targeted therapeutic strategies
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, metastasis, functional genomics, therapeutic target development, and cancer proteomics. Submit a full-length CV, a 3-page future research plan, and the names and contact for 3-5 references Required
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University of Massachusetts Medical School | Worcester, Massachusetts | United States | about 2 hours ago
their therapeutic potential both in vitro and in vivo that includes designing CRISPR-Cas targeting strategies, analyzes editing outcomes on a molecular level using next gen sequencing and ddPCR and conducts
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pathobiology of leukemia, including acute myeloid leukemia (AML) and T cell acute lymphoblastic leukemia (T-ALL), as well as the discovery and validation of new therapy targets to treat relapsed/refractory AML
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of new PET probes that can aid in detecting therapy resistance of various tumor lesions in a patient and new approaches for targeted radioligand therapy. Benefits: 401(k) Dental insurance Flexible schedule
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Investigating signal transduction mechanisms through G protein-coupled receptors and drug discovery. Developing antiviral drug targeting SARS-CoV-2 Nsp1. Designing novel PROTACs (proteolysis targeting chimeras
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research cores that are broadly used, including flow cytometry, CRISPR-Cas9-mediated gene-targeting and computational immunogenomics. The University of Pittsburgh is located in the Oakland and Shadyside
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for cell-type and circuit-specific viral targeting, chemo-/optogenetics, acute slice electrophysiology, in vivo calcium imaging, and operant models of drug self-administration, motivation, cognitive
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to promote tumor growth and to identify the key molecular targets to treat malignancies. His lab is dedicated to translational research, assessing molecular alterations in cancer patient tissues thus obtaining
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to support regulatory measures and policies by the FDA targeting tobacco products. The Jordt lab has pioneered a unique approach combining expertise in sensory neurobiology, addiction, respiratory