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precancers and developing targeted interventions, including vaccines, to intercept them. The project focuses on designing, validating, and preclinically testing neoepitope-based mRNA vaccines to prevent BRCA
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-impact journal articles, particularly targeting evidence-based healthcare design and architectural research. Engage in project dissemination through workshops, conferences, and publications. Undertake
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to characterize the epignetic landscapre of MPN and sAML, uncover the molecular mechanisms underlying disease progression and treatment resistance and identify novel therapeutic targets. You will take a lead on
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culture and organoids to ensure data is clinically relevant. Our overarching aim is to utilise these techniques to identify therapeutic targets to which we can generate effective treatments. The post would
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of selective bioactive molecules targeting transporter proteins, and the design and synthesis of bifunctional molecules for bioorthogonal chemistry, including the synthesis of diazirines, will also be pursued
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renewable award. You will lead a programme of research in the molecular mechanisms of cardiovascular disease, that may include a range of approaches including targeted genetic murine models, primary cell
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pathway, ribosomal translational control and mitochondrial function, and their regulation by PIM kin ases, to further our understanding of PIM kinases in T cells for therapeutic targeting in autoimmune
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facilely applied as a photoluminescent layer, targeting in situ detection and non-contact visualization of surface temperatures and pressures. You should hold a PhD/DPhil (or near completion*) in materials
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-specific molecular pathways can be identified that are suitable as potential drug targets in ARHL. The post-holder will work in the lab of Dr Lisa Nolan to support the development of a single-cell RNA-Seq
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potential drug targets in ARHL. The post-holder will work in the lab of Dr Lisa Nolan to support the development of a single-cell RNA-Seq pipeline for cochlear tissue that is suitable to translate to our