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for health policy decision-making, these methods will be developed using a Bayesian framework. This PhD project will deliver a substantial contribution to original research in the area of health data science
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(NP) led by Professor Jeremy J Baumberg, FRS (https://www.np.phy.cam.ac.uk/ ), as part of UK targeted collaboration on 3D Metamaterials. Metamaterials provide emergent properties by combining nano-scale
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://doi.org/10.1172/jci99169 ). However, a host of interconnected metabolic and immune pathways likely regulate tumour progression. Identification of these novel mechanisms will provide new targeted therapeutic
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, alongside complex drug screening, efficacy and clinical phenotype information. Using these datasets, you will undertake comprehensive strategies aimed at the characterisation and therapeutic targeting
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limited. No immunotherapy for meningiomas has yet gained FDA approval, though early-phase trials targeting IFN-alpha and PD-1 have been conducted. Emerging evidence highlights the crucial role of the immune
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of Health and Life Sciences. Prostate cancer is highly heritable and a good target for genetic risk stratification. Prostate cancer genetic risk scores (GRS) aggregate common variants into a predictive score
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on AI-assisted biocide design to link to their selective membrane targeting and cytotoxicity and a real-world check at Arxada labs based in north Manchester. Completion of some of these training tasks
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. The current PhD projects will partner with researchers in other countries including Mexico and/or Zimbabwe, to run targeted research studies which expand upon the large trials in new cultural contexts (2
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molecular switches that could be targeted by anti-fibrotic drugs. You will master • genome editing, • human iPSC culture and directed differentiation, • live cell biomechanical imaging, and • multiomics
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and clinical phenotype information. Using these datasets, you will undertake comprehensive strategies aimed at the characterisation and therapeutic targeting of medulloblastoma biology, focussing