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, epidemiology. Strong mathematical and quantitative skills. Experience in the implementation of mathematical or statistical models and model fitting, including Bayesian model fitting, is desirable but not
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can be tackled. A video describing the project can be viewed here: https://www.youtube.com/watch?v=IzPuuBnrIDc . The successful candidate will be developing Bayesian models for estimating
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in RA have been improved by the introduction of targeted therapies, disease flare occurs in approximately 50% of patients, negatively impacting quality of life and cumulative joint damage
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. Six siRNA-based therapies are already approved for clinical use. However, a major hurdle in applying siRNA therapeutics to OA is the efficient and targeted delivery of siRNAs to joint-resident cells