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of data matrices (using parsimony and Bayesian phylogenetics); - Conducting multivariate analyses using R. LanguagesENGLISHLevelExcellent Research FieldBiological sciencesEnvironmental science » Earth
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Centre (NCN). The Principal Investigator is Dr. Eng. Piotr Kopka, email: Piotr.Kopka@ncbj.gov.pl Project description: The project aims to develop a new class of inverse Bayesian models called STE-EU-SCALE
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. Knowledge of ensemble reweighting techniques (e.g., Bayesian approaches, metainference) and the ability to assess model-to-data fit quality. Proficiency in Unix/Linux environments and solid programming skills
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, sampling, inference, and machine learning. On one side, statistical approaches such as Bayesian inference play a critical role in identifying the parameters of PDEs, while on the other, newly emerging
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inhibitors lack the specificity needed for precise targeting of this pathway. The current project seeks to address these limitations by developing innovative covalent inhibitors that can specifically target
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mechanisms of α-Syn neurotoxicity and establish P2X7R as a potential therapeutic target in PD. Where to apply E-mail awilkaniec@imdik.pan.pl Requirements Research FieldBiological sciences » OtherEducation
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Project description: The SHIELD consortium targets two closely related steps in the viral replication cycle that are, as yet, difficult to study and to exploit for therapeutic interventions: 1) Virion
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, project leader dr hab. Agnieszka Dzikiewicz-Krawczyk Project title: “Targeting IGH enhancer RNAs as a therapeutic approach in B-cell lymphoma” Research Description: The characteristic feature of several B
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 1 month ago
metastasis. The in vivo function of DDK has remained largely elusive due to past technical constraints. Leveraging our in-house degradable CDC7 mouse models, we are investigating whether targeted CDC7
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receptor (HR+HER2+). These cancers, associated with poor prognosis and high mortality, account for over 50% of breast cancer cases. Current treatment involves chemotherapy, hormonal drugs, and targeted