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uncertainties (delays, resources, failures) using various methods, including Bayesian approaches. 3. Optimize the workshop configuration, taking into account scenario variability, by relying on the surrogate
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maximum likelihood and Bayesian inference frameworks. - Data mining in genome databases. - Large-scale phylogeny reconstruction (archaea, bacteria, and eukaryotes). - Implementation of complex sequence
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experimental parameters (time, temperature). To optimize these parameters, active learning techniques based on Bayesian optimization will be applied. In situ or ex situ characterizations (FTIR, ¹¹B/¹H NMR, HP
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parameter estimation using Bayesian inference, and/or the exploitation of Machine Learning (ML) based algorithms to reduce false positives caused by human generated interference signals in the observational
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uses a tumor-targeting biomolecule (e.g. antibody, peptide, small molecule) labelled with a radionuclide for either diagnostic or therapeutic purposes. Alpha-particle targeted radionuclide therapy (-TRT
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inflammation and immune response and PK dysregulation is well documented in inflammatory pathologies [8-13]. Moreover, several PKs constitute attractive pharmacological targets for therapeutic purposes, as
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, engineering, bioinformatics, machine learning, artificial intelligence) to support minimally invasive and targeted preventive and predictive medicine capable of limiting age-related functional disorders
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Complex sugars (CS) are key ligands for modulating the pharmacological properties of proteins, triggering specific cellular responses, and enabling targeted vectorization in biotherapies. There is therefore
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to its host and its persistence in order to identify potential therapeutic targets. This project aims to identify and validate the function of regulators or actors of specific metabolic pathways using
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gene therapy, vaccine development, and genome-wide CRISPR screens. They a also a promising therapeutic target, as interfering with genome packaging could inhibit viral propagation while reducing the risk