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Research Project Nucleic acids are potent triggers of immune responses. The presence of virus-derived RNA or DNA molecules activates nucleic acid sensors inside the host cell, which stimulates protective
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. These coordinated hormonal activities influence not only the rate of cell division but also the duration and dynamics of each phase of the cell cycle. With the advent of advanced technologies, such as single-cell
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signalling pathways are critical for driving cell cycle progression. These coordinated hormonal activities influence not only the rate of cell division but also the duration and dynamics of each phase
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behavior and circuit integration remains poorly understood. In this project, you will develop and apply spatial transcriptomics methods and combine these with measurements of brain activity and cellular
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). These mutations do not always impair the enzymes’ canonical, ubiquitous functions but instead induce neomorphic activities, such as aberrant transcriptional regulation (Bervoets et al., Nature Communications 2019
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underlying brassinosteroid transport and its coupling with signalling, as well as the roles of phosphorylation in these processes and in the regulation of transporter activity and substrate specificity. We
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, and family situation. We welcome applications from individuals of all backgrounds and identities, and we are dedicated to providing equal opportunities and actively promoting a culture of belonging
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. Ultimately, the goal is to move towards an active-learning-based screening to unravel particular developmental and disease states in its entirety. The automated analysis of this data will be a key building
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at the cellular level, and (iii) applying quantitative image analysis to compare structural organization across fertile and infertile donors. The project is embedded in an active collaboration with a local