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stem cell derivatives. Specifically, the Zani lab investigates the therapeutic potential of stem cell-derived extracellular vesicles (EVs) to regenerate fetal and neonatal hypoplastic lungs. We integrate
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2021, Circulation 2019), 2) Uncovering genetic drivers of anti-cancer drug-induced cardiovascular toxicity through integrated iPSC models and high-throughput CRISPRi/a screening (Cell Stem Cell 2024), 3
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requires working collaboratively with a team of experimental and computational biologists focused on single-nucleus RNA-seq data analysis and “multi-omics” data integration with a main goal to identify
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damage response alterations can be exploited to treat and prevent cancer. The researcher will work with Dr. John Krais and others within the Siteman Cancer Center for Genome Integrity at WashU Medicine