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algorithms to compute similarity between interaction interfaces across millions of comparisons. This hinders identification of novel modes of protein binding, i.e. those predicted by AlphaFold, and it hinders
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their glial niche. Genetically encoded, fluorescent metabolite sensors will be used to study the underlying metabolite dynamics. The work will also incorporate various molecular biology techniques, as
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play a central role in this interdisciplinary initiative. They will: Develop and apply machine learning (ML) methods – including surrogate modeling, feature extraction, and inverse design algorithms
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play a central role in this interdisciplinary initiative. They will: Develop and apply machine learning (ML) methods – including surrogate modeling, feature extraction, and inverse design algorithms