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Medicine, and member of the City of Hope Comprehensive Cancer. The Perry laboratory uses structural biology approaches, together with small molecule and fragment-based drug discovery, computer-aided drug
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: Implement and validate IntelliCage protocols to assess cognition, memory, and social behavior post-injury and post-treatment. Evaluate therapeutic efficacy of NSC- and EV-based interventions in rodent models
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should include: A Ph.D. degree in life or biomedical sciences, or related discipline is required. Experience in pre-clinical, animal models. Experience in microbiome-focused techniques including but not
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therapeutics. Our research involves experiments with RNA Biology, RNA modifications/editing, mRNA-based therapeutics, primary human cancer cells, cancer and stem cell transplantation models, mouse genetics
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. The project involves both in vitro and in vivo studies to uncover the molecular and cellular mechanisms driving cancer-associated immunosuppression using mouse and human solid tumor models. Additionally
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epidemiology, innovative sequencing and bioinformatics technologies including single cell and spatial transcriptomics, molecular biology approaches using cell-based and animal models, and biomarker studies from
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the project for RNA metabolism dysregulation and oncogenesis in blood malignancies. Candidates with strong background in RNA metabolism, cancer biology, and murine model are encouraged to apply
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, comprehensive mouse models for: 1) real-time labeling and lineage tracing 2) inducible and cell type-specific knockout & over-expression 3) inducible deletion of a specific population. We constantly integrate
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on resistance mechanisms in breast cancer, glioblastomas, colon cancer, and lung cancer. Advancing precision oncology through machine-learning models: We integrate multimodal patient data, including multiomic
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qualifications should include: PhD or M.D. with a strong background and profound knowledge in molecular biology, cancer biology, and metabolism. Previous experience in working with animal models of human cancers