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cancer prevention and control education; increase awareness and utilization of resources; and increase community participation in health and biomedical research. Our model is a community participatory
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research project to develop a neoantigen-based cancer vaccines to support an IND utilizing a highly efficient and fully synthetic poxvirus-vectored vaccine platform that has been derisked by its use in Phase
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. The project involves both in vitro and in vivo studies to uncover the molecular and cellular mechanisms driving cancer-associated immunosuppression using mouse and human solid tumor models. Additionally
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or protein structural data analysis is highly preferred. Background with pharmacology, cell therapy or antibody engineering is also desired. · Previous experience in working with animal models
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beta-cells, aiming to identify therapeutic targets for beta-cell regeneration in diabetes. Work with mouse and human cells, mouse models, and stem cells in the context of diabetes, utilizing techniques
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utilizes genetic mouse models, molecular biology, imaging and epigenetic techniques to study the cellular identity, function, remodeling, and survival of beta-cells in physiological and pathological
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cancer. Work in the lab utilizes both genetically engineered mouse models and in vitro systems. A combination of state-of-the-art surgical, genetic, cellular, biochemical, imaging, and metabolic flux
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the BBB and release in vivo where targeted. · Design and validate biochemical and cell-based readouts (including reporter lines) to quantify inhibition of trans-membrane proteins like RAGE and its
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preferred). City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our
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employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer. To learn more about our Comprehensive Benefits, please