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to the role of an Alzheimer’s disease susceptibility factor, CD33, in disease pathogenesis, as well as development of novel CD33-based therapeutics in this context (PMID:35940942). Transgenic models (PMID
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details https://www.pnnl.gov/projects/jgcri ). The Institute focuses on quantitative modeling of Human-Earth systems, primarily to advance the science and inform the policy discussions pertaining
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for the millions living with this disease. Moreover, most islet transplants fail within a few years, requiring patients to return to insulin injections. Two recent advances may transform cell therapy in diabetes
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both in vitro and in vivo models, such as patient-derived organoids and xenografts. We apply molecular profiling (genomics and transcriptomics) along with histological analysis to explore the mechanisms
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optimize sport performance, with preference for projects advancing endurance sport science. Foundational research projects that have indirect ties to sport will be considered if the applicant/supervisor
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fellow will engage in advanced academic research under the supervision of Dr. Alicia Boatswain-Kyte, contributing to the development of scholarly publications, grant applications, and other knowledge
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working with Environment Canada to build better species distribution models that include species interactions and connectivity. The postdoc will develop professionally by learning new statistical techniques
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for vocal learning and performance, songbirds are powerful animal models to reveal the neural mechanisms underlying vocal motor learning and control, including the contribution of PNNs and PV neurons to vocal
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dynamics in models of brain injury and neurodegeneration (amyotrophic lateral sclerosis / ALS and Alzheimer’s disease / AD). Projects will involve in vivo multiphoton imaging of glia, vascular, perivascular
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: - Explore the neurobiology of a biological materials fabrication process using mussels as a model system. - Presenting the results of their work at national and international conferences. - Expected to apply