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epigenetic events, such as enhancer activation and 3D chromatin interactions, that can influence the downstream effects related to the observed changes. Further information can be found at: https://www.crg.eu
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facilities, which currently comprise a room temperature AFM (MFP-3D) and a cryogenic AFM (Attocube). The lab also has a nanoindenter to characterize nanomechanical properties, and familiarity with
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mutations disrupt a lead enhancer controlling a developmental enhancer cluster (Dev Cell, 2022). Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes (Nat
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