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models, 3D co-culture of cancer cells with other compartments of the tumor microenvironment, organoids and/or patient-derived organoids models. Fluorescence microscopy and immunohistochemistry, multiplex
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robust 3D imaging technique suitable across diverse scientific communities. This project has two interconnected aims. The first is to create an accurate “digital twin” of the experiment through end-to-end
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, you are expected to determine the molecular super-structure of TZ. You will monitor the gating mechanism of TZ in cellular models such as RPE1 or cultured dopaminergic neurons by immunofluorescence
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Post-Doctoral Associate in the Center for Translational Medical Devices (Modeling) - Dr. Rafael Song
, cardiovascular, and neurologic disease. These projects entail computational modeling, device design and manufacturing, optimization of chemical, mechanical, and electrical characteristics, and preclinical
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, multi-color flow cytometry, mouse disease models, human patient samples, 3D bone marrow organoid models, single-cell RNA-Sequencing, and general molecular and cellular biology techniques. Working
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, therapeutic development. His lab employs a multidisciplinary approach, comprising biochemistry and cellular biology as well as global transcriptomic, epigenomic, and 3D chromatin structure analyses, using
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, and spatial transcriptomics. Key responsibilities include: Developing AI/ML methods for image alignment across modalities Automated feature detection Predictive modeling of vascularization patterns
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focuses are: 1) Investigating the underlying molecular mechanisms by which 3D genome topology controls the hematopoietic transcription program and lineage differentiation in normal and malignant
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precision cardiovascular medicine, leveraging cutting-edge approaches such as human iPSC-derived 2D cardiovascular cells, 3D vascularized cardioids, CRISPR gene editing, high-throughput CRISPRko/i/a screening
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system The successful candidate will collaborate closely with Dr. Mc Keown and a PhD student to run experiments of CO2 and water sublimation under low pressure conditions, as well as develop 3D topographic